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Introduction. Surgery is the cornerstone in the treatment of rectal cancer. Widespread propagation of standardized total mesorectal excision (TME) has improved overall survival 1, 2.However, TME may be associated with an increased risk of developing anastomotic leakage 3 with attendant morbidity and mortality in the postoperative period 4, 5.Leaks may be associated with decreased local control.
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The DULK score gave an overall sensitivity of 97% for anastomotic leakage, overall specificity of 53%, a positive predictive value (PPV) of 16% and a negative predictive value (NPV) of 99%. The modified DULK score used clinical condition, abdominal pain not localized at the wound, C-reactive protein level and respiratory rate.
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M. den Dulk is supported by a Quality Assurance Fellowship of the European Society of Surgical Oncology. The authors are grateful to Dr. P.J. Breslau for his help with the collection of the retrospective data and want to thank Professor Dr. T. Wiggers, Dr. H.J.T. Rutten, Dr. P.J. Breslau and E. Meershoek-Klein Kranenbarg for their comments on the draft manuscript.
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Allard Den Dulk , Existentialist Engagement in Wallace, Eggers and Foer: A Philosophical Analysis of Contemporary American Literature (London: Bloomsbury, 2015, £62.99). Pp. 301. isbn 978 1 6289 2331 5. - Volume 50 Issue 3
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Aim: This study aimed at testing feasibility of a standardised postoperative surveillance protocol to reduce delay in the diagnosis of anastomotic leakage (AL) and, subsequently, mortality. Material and methods: Patient files of patients operated between 1996 and 1999 were reviewed and used as historical controls (n=1066). As a result, a protocol for standardised post-operative surveillance.
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University of Groningen Microfluidic device Prins, Menno; van der Zaag, Pieter J.; den Dulk, Remco C. IMPORTANT NOTE: You are advised to consult the publisher's.
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den Dulk L, Yerkes MA. Capabilities to combine work and family in the Netherlands: Challenging or reinforcing the one-and-a-half earner model? Kazoku syakaigaku kenkyu. 2016;28(2):180-192. doi: 10.4234/jjoffamilysociology.28.180
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The DULK score gave an overall sensitivity of 97% for anastomotic leakage, overall specificity of 53%, a positive predictive value (PPV) of 16% and a negative predictive value (NPV) of 99%. The modified DULK score used clinical condition, abdominal pain not localized at the wound, C-reactive protein level and respiratory rate.
